While the leading cause of mortality worldwide, it is three to four times more common in diabetics than non-diabetics individuals. Ĭardiovascular disease (CVD) is the most threatening complication of diabetes.
In diabetic patients, oxidative stress is evident within a few years after involvement and before complications become manifest. A significant reduction in the efficiency of antioxidant defenses and/or overproduction of reactive oxygen species (ROS) has a crucial role in the development of the diabetes complications. These aberrancies are almost always accompanied by oxidative stress.
Diabetes mellitus is a chronic hyperglycemic state associated with serious cardiometabolic abnormalities such as insulin resistance, hyperlipidemia, hypertension, and obesity.
